Best Pizza in Central Los Angeles, CA

Authentic Wood Fired Neapolitan Pizza Crafted With Italian Tradition
We Are Located In Los Angeles

We Are Located In Los Angeles

Our Santa Monica Boulevard location at 4959 Santa Monica Boulevard places us in the heart of Los Angeles, surrounded by lively neighborhoods, retail spots, and local attractions. Whether you're visiting from Hollywood, Silver Lake, or nearby areas, we’re easy to find and ready to serve.
Welcome To DeSano Pizzeria Napoletana

Welcome To DeSano Pizzeria Napoletana

Address: 4959 Santa Monica Blvd, Los Angeles, CA 90029, United States Phone: +1 323-913-7000 Hours: Monday 11:30 AM–10 PM Tuesday 11:30 AM–10 PM Wednesday 11:30 AM–10 PM Thursday 11:30 AM–10 PM Friday 11:30 AM–10:30 PM Saturday 11:30 AM–10:30 PM Sunday 11:30 AM–10 PM
Crafted With Fire And Italian Tradition

Crafted With Fire And Italian Tradition

Every creation begins with carefully prepared dough, aged for depth and character, then topped with premium imported ingredients sourced directly from Italy. Fired in authentic wood-burning ovens built with volcanic stone, each pie emerges with a lightly blistered crust, airy interior, and rich layers of flavor. The balance of simplicity and craftsmanship defines every plate—rustic yet refined, bold yet elegant. This is Italian tradition expressed through fire, time, and precision.
Italian Flavors & Enthusiastic Guest Endorsements

Italian Flavors & Enthusiastic Guest Endorsements

In the heart of Los Angeles, our guests celebrate the consistent quality and bold flavors of our signature pies like the Diavola. Semantic trends in reviews point to a high level of satisfaction with the "grand hall" dining experience and the speed of our wood-burning ovens. Local foodies frequently recommend us for our generous toppings and the authentic, chewy-yet-crispy texture of our crust that brings a true taste of Naples to Southern California.

Order From Our Website

Enjoy the same wood-fired craftsmanship from the comfort of your home. Place your order directly through our website for convenient pickup or delivery at your nearest location. Freshly prepared, carefully packaged, and ready when you are.

Experience the visual story of authentic Neapolitan pizza, captured in every frame.

Catering For Every Occasion

Catering For Every Occasion

Freshly prepared, professionally organized, and ready to serve—so your event feels effortless and memorable from start to finish. Let us handle the food while you focus on your guests. Our catering brings authentic wood-fired craftsmanship straight from the oven to your event, whether it’s a corporate lunch, family celebration, birthday party, or special occasion.
A Place For Everyone

A Place For Everyone

Whether you're gathering with family, meeting friends, or planning a casual night out, there’s space and comfort for all. Enjoy relaxed outdoor seating, convenient high chairs for little ones, flavorful vegetarian options, a private dining room for special occasions, and a welcoming atmosphere that’s great for watching sports.

Visit Us Today!! 🍕

Stop by and experience authentic wood-fired Italian craftsmanship at a location near you. We’re conveniently located at 635 U.S. Highway 1 in North Palm Beach, 1012 4th Avenue North in Nashville, 8129 Sawyer Brown Road in Bellevue, 4959 Santa Monica Boulevard in Los Angeles, and across Austin at 301 Lavaca Street Suite 200, 8000 Burnet Road, and 5701 West Slaughter Lane. Wherever you join us, you’ll find the same dedication to quality, tradition, and exceptional service.

What our guests are saying

Fresh, quick, and delicious pizzas! Plenty of room for large parties and the open kitchen is great for watching how they make 'em.

Brett W.

Brett W.

It was super fast! Very similar to the pizzas in Itealy, they even import some of the cheeses from Italy. The pastry was awesome! And aperol spritz is just $8! I will definetly visit it again!

Kagan U.

Kagan U.

I've never had a bad time at DeSano. Hands down one of my favorite pizza spots in town. One of my favorite things is how fast the pizza always comes out. Especially when you come in so hungry and you want to eat immediately. The pizza is always so good. The sauce is great, the cheese they use is great. The place had a parking lot which is always a win in Los Angeles. And they have PLENTY of seating. I will absolutely always say yes if someone invites me here.

Roberto H.

Roberto H.

Featuring

Private Dining Room

Good For Watching Sport

Vegetarian Options

DeSano Pizzeria Napoletana Rewards

Join our rewards program, earn points every time you order online, and redeem your points for free food!

Frequently Asked Questions

What are you known for?
What meals do you serve?

We serve Lunch and Dinner

Do you offer delivery or takeout?

Yes, we offer Takeout and Delivery

What areas do you serve?

Our locations